Genetic diversity and genetic distance of five populations of the Nigerian breeds of goat were investigated using random amplified polymorphic DNA markers. Five breeds of goat were used for the study and each breed constituted a population, hence, the five populations considered in the study. The populations were: Sokoto Red (SR), Sahel (SH), Kano Brown(KB), Bornu White (BW) and West African Dwarf (WAD) goats. The experiment was conducted within four geographical zones of Nigeria: South east, North west, North east and North central. One hundred and twenty (120) blood samples were randomly collected from various locations across the four geographical zones in Nigeria. The samples were collected from the stocks at the central markets, which served as collection point from all the localities and from household goat keepers.