Macrophyte distribution in relation to water quality parameters in roadside ponds was studied in a seasonal wetland at Mkpat EninLocal Government Area of Akwa Ibom State. Systematic sampling method was used in sampling the vegetation using a quadrant of 5mx5m space at regular intervals. The vegetation parameters such as density and frequency were determined. Water sample was also collected at different point in the pond and their physiochemical characteristic were analysed. Ten (10) flora species belonging to 10 families were recorded. Cryptosperma senegalense was the species with the highest richness with density value of (9500±150.63st/ha) and this followed by Nymphea lotus (6000±138.36st/ha). The least density value was associated with Alchornea cordifolia (300±43.54st/ha). Crypstosperma senegalense also had the highest frequency (100%) while the least frequency value of 25% was associated with species such as Alchornea cordifolia, Heteranthera cordifolia, Lygodium sp. and physalis angulata respectively. This study shows that water properties have substantial effect on the distribution of macrophyte species and that the density of each species correlated positively or negatively with water parameters. The study provides a baseline information towards the monitoring and management of ponds and other wetland ecosystems within the State.