This study was carried out to examine the statistical analysis on the impact of birth and death rates on Nigeria economy from 1990 – 2018. To achieve this objective, three research questions and two research hypotheses were formulated to guide this study. The data was collected from secondary sources. The secondary data were collected with the help of WHO Statistical Bulletin and other journals and articles. The data collected were analyzed using regressional analysis to test research hypotheses. The study reveals that there is a significant relationship between birth rate and the economy of Nigeria from 1990 – 2018 and there is a significant relationship between death rate and the economy of Nigeria. The concluded with some recommendations that the policies to enhance export should be adopted to promote export growth in Nigeria since it enhances the rate of economic growth in Nigeria and the Nigerian economy should be diversified to enhance productivity of labour and economic growth as life expectancy increases.