AbstractUrban areas are suffering from the problem of ever-increasing population and consequently inadequate food supply. This study attempts to identify determinants of food security in Wolaita Sodo town at the female-headed household level. Household calorie acquisition was analyzed to measure the status of household food security. Based on the survey result of 80 female-headed households, the logistic model was estimated. Results indicate that variables related to the age of household head, educational level of household head, size of the family (AE), possessing asset, number of the active labor force available in the household, the health status of the household head, and practicing urban agriculture was found to be a statistically significant predictor of household food security in the study area. It was recommended that development interventions like effective family planning strategies and capacity building for older female household heads will immensely contribute to the attainment of food security. In general, the results of the study produce the implication that attaining food security in the urban areas of Ethiopia requires the adoption of mixed strategies and policies.