This work was carried out to investigate the phytochemical and proximate analysis of the effect of Burantashi stem on Erectile dysfunction. Burantashi is a popular seasoning agent to barbecued meat (suya) in Nigeria, found in the northern part of the country. Erectile dysfunction (ED) is defined as the consistent or recurrent inability of a man to attain or maintain penile erection, sufficient for sexual activity (2nd International Consultation on Sexual Dysfunction – Paris, June 28th – July 1st, 2003). Following the discovery and introduction of Burantashi research on the mechanism underlying penile erection, has had an enormous boost and many preclinical and clinical papers have been published in the last five years on the peripheral regulation of, and the mediators involved in human penile erection. The most widely accepted risk factors for ED are discussed. The research is focused on human data and the safety and effectiveness of Burantashi stem as a Phosphodiesterase - 5 inhibitors (PDE5) used to treat Erectile Dysfunction.