ABSTRACT   According to research studies into the relationship between a worker’s life and his job, stress is assuming a position as number one killer disease in the modern society.  The purpose of his work was to find out the effects of stress on the secretary’s job performance, what factors caused this stress and how their effects were manifested and could be controlled. To do this, literature review relating to the effects of stress on the workers especially the sedentary worker, was conducted.  A questionnaire was drawn up with which data were collected.  This was supplemented by face-to-face interviews with secretaries and observations.  The respondents were from Anammco Company and Emenite Aluminium Company, Enugu.  In all, 100 questionnaires wee distributed and 88 were returned while 12 were not returned. The researcher from data analysis found out that secretaries under-face a lot of stressing situations in the course of doing their job but that some were more devastating in the effects than others.  The three most significant stressors identified were:   1. Lack of adequate and sufficient working materials and equipment. 2. Strenous human relation in the workplace and 3. lack of necessary qualification, both physically and mentally on the part of the secretary to handle the job efficiently. Recommendation were however made that adequate training of the secretary physically and mentally should be provided.  Provision of good working materials for the secretary as well as adequate co-operation from the boss will help to go a long way in helping reduce the stressful situation in the secretary’s job.

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