BIOCHEMISTRY PROJECT TOPICS AND RESEARCH MATERIALS

• 181. PHYTOCHEMICAL ANALYSIS AND THE ANTI- INFLAMMATORY ACTIVITIES OF METHANOL EXTRAC...

  » ABSTRACT Inflammation is a complex biological response of vascular tissue to harmful stimuli such as pathogen, damage cells or irritants. The urgency generated by in increased rate of stroke, atheroselerosis attributed to prolong use of cyclooxygenase 1 and 2 inhibitors have acceralated anti inflammatory drug research over the last decade while synthetic pharmaceutical agents continued to dominate...Continue Reading »

  50 pages |  -1 engagements | 

• 182. PHYTOCHEMICAL ANALYSIS AND THE ANTI- INFLAMMATORY ACTIVITIES OF DICHLOROMETHANE ...

  » ABSTRACT Inflammation is a complex biological response of vascular tissue to harmful stimuli such as pathogen, damage cells or irritants (Ryan & Majno, 1983). The urgency generated by increased rate of stroke, atherosclerosis attribute due to prolonged use of cyclooxygenase 1 and Cyclooxygenase 2 inhibitors have accelerated anti inflammatory drug research over the last decade while synthetic p...Continue Reading »

  50 pages |  -1 engagements | 

• 183. PARTIAL PURIFICATION AND EFFECT OF TEMPERATURE AND HEAT STABILITY STUDIES ON RH...

  » ABSTRACT The research is aimed at investigating the effect of temperature and heat stability of Rhodanese from the Liver of a local goat. This research shows the existence of rhodanese from a local goat liver homogenate. It was observed that the enzyme was partially purified by ammonium sulphate precipitation and dialysis. The specific activity of enzyme after partial purification using ammonium s...Continue Reading »

  50 pages |  -1 engagements | 

• 184. NUTRITIONAL POTENTIAL OF SYNSEPALUM DULCIFICUM PULP AND THE EFFECTOF THE METHAN...

  » ABSTRACT The nutritive and antinutritive compositions of S. dulcificum pulp were analysed to augment the available information on the anti diabetic effect of the plant. Biochemical parameters like liver function enzymes (ALT, AST, ALP) and bilirubin concentrations,serum total protein, serum albumin and globulin, kidney function parameters (creatinine and urea concentrations), blood glucose, serum ...Continue Reading »

  50 pages |  -1 engagements | 

• 185. MODULATION OF IMMUNOLOGICAL RESPONSES IN ALBINO RATS BY LEAF EXTRACTS OF TELFAI...

  » ABSTRACT The immuno modulating effects of leaf extracts of Telfairia occidentalis (Hook F) and Tectona grandis (Linn) on both humoral and cell mediated immune responses were evaluated in vivo. The responding cells were defined by flow cytometry and secretion of various cytokines by ELISA. Structural elucidation of the bioactive molecules responsible for the observed effect was equally attempted. R...Continue Reading »

  50 pages |  -1 engagements | 

• 186. LEVELS OF POLYCYCLIC AROMATIC HYDROCARBON IN FRESH WATER FISH DRIED UNDER DIFFE...

  » ABSTRACT Preservation of fish by drying over different types of heat regimes have been known. However, there has not been a comprehensive comparison in terms of the possible contamination associated with these drying regimes. This work was set to evaluate the levels of PAHs that are likely to accumulate in the bodies of fresh water fishes dried under heat from charcoal, sun (sun drying), electric ...Continue Reading »

  50 pages |  -1 engagements | 

• 187. EVALUATION OF THE ANTIDIABETIC EFFECTS OF WATER AND METHANOLIC EXTRACTS OF AVOC...

  » ABSTRACT The high prevalence, complications and cost of conventional drugs in the management diabetes necessitated the search for alternative treatment. As a result, this study seeks to evaluate the composition, anti diabetic potential toxicity and tissue protective effects of both the water and methanolic extracts of Persea americana (avocado pear) seed on alloxan induced diabetic albino rats wer...Continue Reading »

  50 pages |  -1 engagements | 

• 188. EVALUATION OF ANTIOXIDANT POTENTIAL OF MONODORA MYRISTICA (AFRICAN NUTMEG)

  » ABSTRACT This work evaluates the antioxidant potential of Monodora myristica (African nutmeg). Monodora myristica extract was obtained by solvent extraction using n hexane and used as treatment on freshly prepared crude palm kernel oil and palm oil. Equal volume of oil samples were subjected to different concentration of extract treatment (0.2ml,0.4ml, 0.6ml, 0.8ml, 1.0ml using syringe. These oil ...Continue Reading »

  50 pages |  -1 engagements | 

• 189. ELEMENTAL ANALYSIS ON PTEROCARPUS MILDBREADII (OHA) SEED PRESENTED

  » ABSTRACT Elemental analysis is the qualitative detection and quantitative determination of chemical elements(atoms,ions)in a sample(Fritz Pregl 1923). To detect an element, one should fix an appearance of an analytical signal. The formation of precipitate or characteristic crystals, colour change, an isolation of gaseous products, an appearance of a definite lines in spectrum, luminescence, etc. T...Continue Reading »

  50 pages |  444 engagements | 

• 190. EFFECTS OF QUAIL (COTURNIX JAPONICA)EGGDIET ON BLOOD SUGAR AND LIPID PROFILELEV...

  » ABSTRACT Egg consumption is a popular choice for good nutrients, but by far the egg most often consumed by human is the chicken egg, typically unfertilized. Quail eggs help treat tuberculosis, asthma, and diabetes and it can also help prevent kidney, liver, or gallbladder stones. Thus, this study is aimed at determining quail egg’s dietary effect on the blood sugar and lipid profile of allox...Continue Reading »

  50 pages |  -1 engagements | 

• 191. EFFECTS OF PROCESSING METHODS ON THE PHYSICO-CHEMICAL PROPERTIES OF SWEET POTAT...

  » ABSTRACT This study evaluated “the effects of processing methods on the physico chemical properties of sweet potato and sorghum flour”. Sweet potato (Ipomoea batatas) is an important food crop in the tropical and sub tropical countries and belongs to the family convolvulaceae. Sweet potatoes are rich in dietary fiber, minerals, vitamins, and anti oxidants such as phenolic acids, anthoc...Continue Reading »

  50 pages |  -1 engagements | 

• 192. EFFECTS OF ETHANOL, METHANOL AND N-HEXANE LEAF AND FRUIT EXTRACTS OF Kigelia af...

  » ABSTRACT Globally, the estimated incidence of diabetes and projection for the year 2030 as given by the International Diabetes Federation (IDF) is 350 million. Kigelia africana is highly used for ethnomedicinal purposes although there is paucity of scientific information on its use. This work was therefore, aimed at evaluating the anti diabetic and antioxidative potential of the plant. Ethanol, me...Continue Reading »

  50 pages |  -1 engagements | 

• 193. EFFECTS OF ALCOHOL ON SOME BIOCHEMICAL PARAMETERS OF ALCOHOLICS IN NSUKKA, ENUG...

  » ABSTRACT This work was aimed at finding the effects of alcohol on some biochemical parameters. A total of one hundred and eighty (180) apparently healthy, non hypertensive male alcoholics were used for the study. Forty (40) non consumers of alcohol were used as control. The activity of alanine aminotransferase (ALT) in the control was 10.50±2.00 IU/L while it was 16.50±1.50 IU/L; 17....Continue Reading »

  50 pages |  774 engagements | 

• 194. EFFECT OF TELFERIA OCCIDENTALIS AND VERNONIA AMYGDALINA ON LIVER, HEART AND PL...

  » ABSTRACT Sixty (60) albino rats of the wistar strain were used to investigate the effect different vegetables extracts modified diets; shared into two groups, one part fed with high sucrose diet while others were fed with normal ratchow. Electrolytes status were analysed in the plasma, liver and heart after four weeks of feeding. The liver being the organ where major metabolisms take place and the...Continue Reading »

  50 pages |  -1 engagements | 

• 195. EFFECT OF TELFERIA OCCIDENTALIS AND VERNONIA AMYGDALINA ON LIVER FUNCTION TEST ...

  » ABSTRACT Vegetables and fruit provide a significant part of human nutrition, as they are important sources of nutrients, dietary fibre, and phytochemicals. Sixty (60) albino rats were used to study the effect vegetables extracts modified diets; grouped into, one group was fed with high sucrose diet while others were fed with normal ratchow. After 3weeks of feeding respective vegetable extracts w...Continue Reading »

  50 pages |  -1 engagements | 

• 196. EFFECT OF TELFERIA OCCIDENTALIS AND VERNONIA AMYGDALINA ON LIPID PROFILE (TOTAL...

  » ABSTRACT Sixty (60) albino rats of the wistar strain were used to investigate the effect different vegetables extracts modified diets; shared into two groups, one part fed with high sucrose diet while others were fed with normal ratchow. Lipid profile status were analysed in the plasma, brain and kidney after four weeks of feeding. The brain revealed a significant (p<0.05) decrease in triglycer...Continue Reading »

  50 pages |  -1 engagements | 

• 197. EFFECT OF TELFERIA OCCIDENTALIS AND VERNONIA AMYGDALINA ON ELECTROLYTES (CALCIU...

  » ABSTRACT Sixty (60) albino rats of the wistar strain were used to investigate the effect different vegetables extracts modified diets; shared into two groups, one part fed with high sucrose diet while others were fed with normal ratchow. Electrolytes status were analysed in the plasma, liver and heart after four weeks of feeding. Feeding of rats with high sucrose diet revealed a significant (p<...Continue Reading »

  50 pages |  -1 engagements | 

• 198. EFFECT OF METAL IONS ON ARGINASE FROM THE KIDNEY OF LOCAL GOAT (Capra aegagrus...

  » ABSTRACT This research is aimed at isolating, partially purifying and determination of arginase from the kidney of a local goat. Methods used in the isolation and partial purification of the enzyme include; Ammonium sulphate precipitation, dialysis.etc. Result from this work showed that arginase isolated from a local goat has a specific activity of 0.358 with a yield of 12.12% incubation of the en...Continue Reading »

  50 pages |  -1 engagements | 

• 199. EFFECT OF CONTROLLED FERMENTATION USING ASPERGILLUS NIGER AND TRICHODERMA HARZA...

  » CHAPTER 1 INTRODUCTION The genus Indigofera Linn. is a large genus of about 700 species of flowering plants belonging to the sub family Papilionoideae in the family Fabaceae / Leguminosae. They occur throughout the tropical and subtropical regions of the world. Burkill (1995) recognized 60 species while Soladoye and Lewis (2003) recorded 60 species in Nigeria with over 60% abundance in the Norther...Continue Reading »

  50 pages |  -1 engagements | 

• 200. EEFECTS OF TELFERIA OCCIDENTALIS AND VERNONIA AMYGDALINA ON ANTIOXIDANTS (SUPER...

  » ABSTRACT This study was aimed at investigating the effect of vegetable extract (Juice and pulp) on oxidative stress induced by high sucrose diets on specific antioxidants such as (Catalase, Superoxide Dismutase (SOD) and Malondiadehyde (MDA) in the liver, brain and plasma. 60 albino wistar strain rats were used, The rats were shared into two groups, one part fed with high sucrose diet while others...Continue Reading »

  50 pages |  384 engagements |